Adhesion molecules in the regulation of autoimmunity

Adhesion molecules in the regulation of autoimmunity

Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin.

1992 Yednock, T.A., Cannon, C., Fritz, L.C., Sanchez-Madrid, F., Steinman, L. & Karin, N. Nature 356, 63-66. (1992).
This Nature manuscript led to the development of the leading drug to Muliple Sclerosis.