Exploring the role of chemokines in cancer diseases

Exploring the role of chemokines in cancer diseases

Three years ago Liat Izhak, at that time a Ph.D. student in the lab, discovered that one of the major chemokines named CCL2 is essential for the development of cancer of the prostate since it directs the migration of bone marrow derived monocytic cells to the tumor site to support tumor angiogenesis (Izhak et al J. Immunol 2009; Izhak et al J. Immunol 2010), and later used highly sophisticated techniques to follow the in vivo dynamics of this process (Izhak et al, Plos One 2012). The lab is intensively investigating the indirect role of other chemokines in cancer developmenent and spread.